Hugging Face 联合发布 14.8B 开源 DNA 语言模型 Carbon-X

We use cookies on our website to give you the most relevant experience by remembering your preferences and repeat visits. By clicking “Accept”, you consent to the use of ALL the cookies. .

Cookie settings REJECT ACCEPT

Necessary Always Active

Necessary cookies are absolutely essential for the website to function properly. This category only includes cookies that ensures basic functionalities and security features of the website. These cookies do not store any personal information.

Cookie __cf_bm
Duration 1 hour
Description This cookie, set by Cloudflare, is used to support Cloudflare Bot Management.
Cookie _pxvid
Duration 1 year
Description PerimeterX sets this cookie to detect fraud and bot activity.
Cookie _px3
Duration 6 minutes
Description This cookie is set by the Bloomberg to protect the site from BOT attacks.
Cookie CookieLawInfoConsent
Duration 1 year
Description CookieYes sets this cookie to record the default button state of the corresponding category and the status of CCPA. It works only in coordination with the primary cookie.
Cookie cookielawinfo-checkbox-necessary
Duration 11 months
Description This cookie is set by GDPR Cookie Consent plugin. The cookies is used to store the user consent for the cookies in the category "Necessary".
Cookie cookielawinfo-checkbox-others
Duration 1 year
Description Set by the GDPR Cookie Consent plugin, this cookie stores user consent for cookies in the category "Others".
Cookie cookielawinfo-checkbox-non-necessary
Duration 11 months
Description This cookie is set by GDPR Cookie Consent plugin. The cookies is used to store the user consent for the cookies in the category "Non Necessary".
Cookie cookielawinfo-checkbox-analytics
Duration 1 year
Description Set by the GDPR Cookie Consent plugin, this cookie records the user consent for the cookies in the "Analytics" category.
Cookie cookielawinfo-checkbox-performance
Duration 1 year
Description Set by the GDPR Cookie Consent plugin, this cookie stores the user consent for cookies in the category "Performance".
Cookie cookielawinfo-checkbox-uncategorized
Duration 1 year
Description The cookie is set by the GDPR Cookie Consent plugin to record the user consent for cookies in the category "Uncategorized".
Cookie cookielawinfo-checkbox-functional
Duration 1 year
Description The GDPR Cookie Consent plugin sets the cookie to record the user consent for the cookies in the category "Functional".
Cookie cookielawinfo-checkbox-advertisement
Duration 1 year
Description Set by the GDPR Cookie Consent plugin, this cookie records the user consent for the cookies in the "Advertisement" category.
Cookie wpEmojiSettingsSupports
Duration session
Description WordPress sets this cookie when a user interacts with emojis on a WordPress site. It helps determine if the user's browser can display emojis properly.
Cookie VISITOR_PRIVACY_METADATA
Duration 6 months
Description YouTube sets this cookie to store the user's cookie consent state for the current domain.
Cookie viewed_cookie_policy
Duration 11 months
Description The cookie is set by the GDPR Cookie Consent plugin and is used to store whether or not user has consented to the use of cookies. It does not store any personal data.
Cookie PHPSESSID
Duration
Description This cookie is native to PHP applications. The cookie is used to store and identify a users' unique session ID for the purpose of managing user session on the website. The cookie is a session cookies and is deleted when all the browser windows are closed.
Cookie __cfduid
Duration 4 weeks
Description The cookie is set by CloudFare. The cookie is used to identify individual clients behind a shared IP address d apply security settings on a per-client basis. It doesnot correspond to any user ID in the web application and does not store any personally identifiable information.

Functional

Functional cookies help to perform certain functionalities like sharing the content of the website on social media platforms, collect feedbacks, and other third-party features.

Cookie yt-remote-connected-devices
Duration never
Description YouTube sets this cookie to store the user's video preferences using embedded YouTube videos.
Cookie ytidb::LAST_RESULT_ENTRY_KEY
Duration never
Description The cookie ytidb::LAST_RESULT_ENTRY_KEY is used by YouTube to store the last search result entry that was clicked by the user. This information is used to improve the user experience by providing more relevant search results in the future.
Cookie yt-remote-device-id
Duration never
Description YouTube sets this cookie to store the user's video preferences using embedded YouTube videos.
Cookie yt-remote-session-name
Duration session
Description The yt-remote-session-name cookie is used by YouTube to store the user's video player preferences using embedded YouTube video.
Cookie yt-remote-fast-check-period
Duration session
Description The yt-remote-fast-check-period cookie is used by YouTube to store the user's video player preferences for embedded YouTube videos.
Cookie yt-remote-session-app
Duration session
Description The yt-remote-session-app cookie is used by YouTube to store user preferences and information about the interface of the embedded YouTube video player.
Cookie yt-remote-cast-available
Duration session
Description The yt-remote-cast-available cookie is used to store the user's preferences regarding whether casting is available on their YouTube video player.
Cookie yt-remote-cast-installed
Duration session
Description The yt-remote-cast-installed cookie is used to store the user's video player preferences using embedded YouTube video.
Cookie na_id
Duration 1 year
Description This cookie is set by Addthis.com to enable sharing of links on social media platforms like Facebook and Twitter
Cookie vc
Duration 1 year
Description This cookie is set by addthis.com on sites that allow sharing on social media.
Cookie __atuvc
Duration 1 year
Description This cookie is set by Addthis to make sure you see the updated count if you share a page and return to it before our share count cache is updated.
Cookie __atuvs
Duration 30 minutes
Description This cookie is set by Addthis to make sure you see the updated count if you share a page and return to it before our share count cache is updated.
Cookie ouid
Duration 1 year
Description The cookie is set by Addthis which enables the content of the website to be shared across different networking and social sharing websites.

Analytics

Analytical cookies are used to understand how visitors interact with the website. These cookies help provide information on metrics the number of visitors, bounce rate, traffic source, etc.

Cookie ga*
Duration 1 year 1 month 4 days
Description Google Analytics sets this cookie to store and count page views.
Cookie _ga
Duration 2 years
Description This cookie is installed by Google Analytics. The cookie is used to calculate visitor, session, camapign data and keep track of site usage for the site's analytics report. The cookies store information anonymously and assigns a randoly generated number to identify unique visitors.
Cookie sbjs_migrations
Duration session
Description Sourcebuster sets this cookie to identify the source of a visit and stores user action information in cookies. This analytical and behavioural cookie is used to enhance the visitor experience on the website.
Cookie sbjs_current_add
Duration session
Description Sourcebuster sets this cookie to identify the source of a visit and stores user action information in cookies. This analytical and behavioural cookie is used to enhance the visitor experience on the website.
Cookie sbjs_first_add
Duration session
Description Sourcebuster sets this cookie to identify the source of a visit and stores user action information in cookies. This analytical and behavioural cookie is used to enhance the visitor experience on the website.
Cookie sbjs_current
Duration session
Description Sourcebuster sets this cookie to identify the source of a visit and stores user action information in cookies. This analytical and behavioural cookie is used to enhance the visitor experience on the website.
Cookie sbjs_first
Duration session
Description Sourcebuster sets this cookie to identify the source of a visit and stores user action information in cookies. This analytical and behavioural cookie is used to enhance the visitor experience on the website.
Cookie sbjs_udata
Duration session
Description Sourcebuster sets this cookie to identify the source of a visit and stores user action information in cookies. This analytical and behavioural cookie is used to enhance the visitor experience on the website.
Cookie sbjs_session
Duration 1 hour
Description Sourcebuster sets this cookie to identify the source of a visit and stores user action information in cookies. This analytical and behavioural cookie is used to enhance the visitor experience on the website.
Cookie tk_or
Duration 1 year 1 month 4 days
Description JetPack plugin sets this referral cookie on sites using WooCommerce, which analyzes referrer behaviour for Jetpack.
Cookie tk_r3d
Duration 3 days
Description JetPack installs this cookie to collect internal metrics for user activity and improve user experience.
Cookie tk_lr
Duration 1 year
Description JetPack plugin sets this referral cookie on sites using WooCommerce, which analyzes referrer behaviour for Jetpack.
Cookie tk_ai
Duration 1 year
Description JetPack sets this cookie to store a randomly-generated anonymous ID used only within the admin area and for general analytics tracking.
Cookie tk_tc
Duration session
Description JetPack sets this cookie to record details on how users use the website.
Cookie _gat_gtag_UA_5784146_31
Duration 1 minute
Description Google Used to distinguish users.
Cookie GPS
Duration 30 minutes
Description This cookie is set by Youtube and registers a unique ID for tracking users based on their geographical location
Cookie __gads
Duration 2 years
Description This cookie is set by Google and stored under the name dounleclick.com. This cookie is used to track how many times users see a particular advert which helps in measuring the success of the campaign and calculate the revenue generated by the campaign. These cookies can only be read from the domain that it is set on so it will not track any data while browsing through another sites.
Cookie uvc
Duration 1 year
Description The cookie is set by addthis.com to determine the usage of Addthis.com service.
Cookie ad-id
Duration 7 months
Description Provided by amazon-adsystem.com for tracking user actions on other websites to provide targeted content
Cookie _gat_gtag_UA_116563943_1
Duration 1 minute
Description Google uses this cookie to distinguish users.
Cookie _gid
Duration 1 day
Description This cookie is installed by Google Analytics. The cookie is used to store information of how visitors use a website and helps in creating an analytics report of how the wbsite is doing. The data collected including the number visitors, the source where they have come from, and the pages viisted in an anonymous form.

Performance

Performance cookies are used to understand and analyze the key performance indexes of the website which helps in delivering a better user experience for the visitors.

Cookie YSC
Duration
Description This cookies is set by Youtube and is used to track the views of embedded videos.
Cookie _gat
Duration 1 minute
Description This cookies is installed by Google Universal Analytics to throttle the request rate to limit the colllection of data on high traffic sites.

Advertisement cookies are used to provide visitors with relevant ads and marketing campaigns. These cookies track visitors across websites and collect information to provide customized ads.

Cookie COMPASS
Duration 1 hour
Description The COMPASS cookie is used by Yahoo to deliver targeted advertising based on user's online behavior.
Cookie NID
Duration 5 months
Description This cookie is used to a profile based on user's interest and display personalized ads to the users.
Cookie __Secure-YNID
Duration 6 months
Description Google cookie used to protect user security and prevent fraud, especially during the login process.
Cookie __Secure-ROLLOUT_TOKEN
Duration 6 months
Description YouTube sets this cookie to manage feature rollout and experimentation. It helps Google control which new features or interface changes are shown to users as part of testing and staged rollouts, ensuring consistent experience for a given user during an experiment.
Cookie yt.innertube::nextId
Duration never
Description YouTube sets this cookie to register a unique ID to store data on what videos from YouTube the user has seen.
Cookie yt.innertube::requests
Duration never
Description YouTube sets this cookie to register a unique ID to store data on what videos from YouTube the user has seen.
Cookie VISITOR_INFO1_LIVE
Duration 5 months
Description This cookie is set by Youtube. Used to track the information of the embedded YouTube videos on a website.
Cookie TapAd_TS
Duration 1 month
Description The cookie is set by Tapad.com. The purpose of the cookie is to track users across devices to enable targeted advertising.
Cookie TapAd_DID
Duration 1 month
Description The cookie is set by tapad.com. The purpose of the cookie is to track users across devices to enable targeted advertising
Cookie personalization_id
Duration 2 years
Description This cookie is set by twitter.com. It is used integrate the sharing features of this social media. It also stores information about how the user uses the website for tracking and targeting.
Cookie uid
Duration 1 year
Description This cookie is used to measure the number and behavior of the visitors to the website anonymously. The data includes the number of visits, average duration of the visit on the website, pages visited, etc. for the purpose of better understanding user preferences for targeted advertisments.
Cookie loc
Duration 1 year
Description This cookie is set by Addthis. This is a geolocation cookie to understand where the users sharing the information are located.
Cookie IDE
Duration 2 years
Description Used by Google DoubleClick and stores information about how the user uses the website and any other advertisement before visiting the website. This is used to present users with ads that are relevant to them according to the user profile.
Cookie di2
Duration 1 year
Description This cookie is set by addthis.com on sites that allows sharing on social media. The cookie is used to track user behavior anonymously to generate usage trends to improve relevance to their services and advertising.

Others

Other uncategorized cookies are those that are being analyzed and have not been classified into a category as yet.

Cookie pxcts
Duration session
Description Description is currently not available.
Cookie _pxttld
Duration session
Description Description is currently not available.
Cookie SGPBShowingLimitationDomain77659
Duration 2 days
Description Description is currently not available.
Cookie __Secure-YEC
Duration past
Description YouTube sets this cookie to stores the user's video player preferences using embedded YouTube video
Cookie S
Duration 1 hour
Description Used by Yahoo to provide ads, content or analytics.
Cookie test_cookie
Duration 11 months
Description This cookie is set by doubleclick.net. The purpose of the cookie is to determine if the users' browser supports cookies.
Cookie sc_at
Duration 1 year
Description Snapchat sets this cookie for showing relevant advertising based on the user’s movement.
Cookie TapAd_3WAY_SYNCS
Duration 1 month
Description TapAd sets this cookie for data synchronization with advertising networks.
Cookie _pin_unauth
Duration 1 year
Description Pinterest set this cookie to group actions for users who cannot be identified.
Cookie sc_anonymous_id
Duration 9 years
Description Soundcloud sets this cookie to enable visitors to embed content or files on the website.
Cookie um
Duration 1 year
Description Set by addthis.com.(Purpose not known)
Cookie DCRP_Categories
Duration 4 weeks
Description Description is currently not available.
Cookie vuid
Duration 2 years
Description Vimeo installs this cookie to collect tracking information by setting a unique ID to embed videos on the website.
Cookie X-AB
Duration 1 day
Description Adobe Analytics sets this cookie in context with multi-variate testing. This is a tool used to combine or change content on the website. This allows the website to find the best variation or edition of the site.
Cookie YTC
Duration 10 minutes
Description YouTube sets the YTC cookie to manage the embed and viewing of videos on the website.
Cookie sp_t
Duration 1 month
Description The sp_t cookie is set by Spotify to implement audio content from Spotify on the website and also registers information on user interaction related to the audio content.
Cookie sp_landing
Duration 1 day
Description The sp_landing is set by Spotify to implement audio content from Spotify on the website and also registers information on user interaction related to the audio content.
Cookie __asc
Duration 30 minutes
Description Alexa Metrics sets this cookie to track and report information to the Alexa analytics service.
Cookie __auc
Duration 1 year
Description Alexa Metrics sets this cookie to track and report information to the Alexa analytics service.
Cookie AWSESS
Duration
Description Awin sets this to ensure the same kind of advertisement is not shown to the user.
Cookie nevercache-b39818
Duration session
Description Description is currently not available.

REJECT Save My Preferences ACCEPT

Image 4: Logo News Hub

Premium Content

Read our exclusive articles

Facebook

Instagram

Discord Linkedin Reddit X

Image 5: Logo News Hub

Image 6: Logo MARKTECHPOST

Search AI news...

Home Editors Pick Agentic AIHugging Face Releases Carbon-X, a 14B Open DNA Language Model that Brings...

Hand AI the chore. It gets it done. We gave it a wallet to pay its way on the web.Activate your wallet**→The job application Working✓ Filled Forgotten subscriptions Working✓ Found Snack sign-up form Working✓ Shared eBay price check Working✓ Checked300,000+ users** · +30% top-up bonus through Oct 31 Sponsored

Hugging Face Releases Carbon-X, a 14B Open DNA Language Model that Brings DNA and Natural Language Together for the First Time

Asif Razzaq

October 25, 2026

Add as a preferred source on Google

Hugging Face has released Carbon-X, an open DNA language model with 14.8B parameters. Carbon-X is a decoder-only model from Hugging Face Bio. It reads raw DNA in a chat and answers in English. It predicts whether mutations are benign or pathogenic, flags regulatory regions, classifies organisms and predicts next bases. The weights ship under Apache 2.0, so labs can keep sensitive sequences on their own GPUs. Hugging Face built it with Zhongguancun Academy and TIGEM / University of Naples Federico II.

TL;DR

Size: 14.8B parameters (dense, no MoE), 40,960-token context.
Runs on: 1 x 80 GB GPU in bfloat16 via vLLM or Transformers. Official GGUF: Q8_0 is 15.8 GB, Q4_K_M is 9.6 GB.
Performance: 66.7% average on 5 DNA benchmarks, best of every open model tested (self-reported).
Best: 74.9% on BioReason Coding, ahead of every model tested, open or closed.
Worst: 29.8% on GenomeQA splice-site questions.

What is Carbon-X and how does it work?

Carbon-X starts from Qwen3-14B. DNA and text share 1 token stream in 1 decoder. There is no separate DNA encoder, unlike earlier work such as BioReason.

**TEXTTABLELAYOUTIs your PDF parser actually getting it right? none omni_parse_bench · scores text, tables & layout · open source Star on GitHub→**Sponsored

The key structure piece is a hybrid tokenizer. It keeps Qwen3’s BPE vocabulary for text and adds 5,515 DNA tokens. These include 4,096 non-overlapping 6-mers, 1,364 tail tokens and 3 markers. One DNA token covers 6 base pairs. DNA runs of 6 or more A/C/G/T bases are tagged automatically.

The backbone is a standard Qwen3 stack. It has 40 layers, hidden size 5120 and GQA with 8 KV heads.

How was Carbon-X trained?

Training ran in four stages, per the model card:

Embedding warmup: about 10B tokens with the transformer frozen, so only the new DNA embeddings learn.
Mid-training: 302B tokens at 8,192 sequence length. The mix is 55% raw DNA, 20% English, 15% biology text and 10% instruction data.
SFT: 3 epochs over 20 dataset subsets, with responses checked by deterministic verifiers built with domain experts.
RL: asynchronous GRPO with verifiable rewards over 2 rounds, using TRL and vLLM.

As per the release post, learning rate was the hardest knob. High rates learned DNA but forgot English. A lower rate, a 14B model and a long run fixed the trade-off. RL applied directly to Qwen3-14B never beat the 50% chance baseline on FrontierVEP.

100K 200K 300K+users hand AI their chores.+30% wallet bonus · ends Oct 31 Claim 30% bonus**→**Sponsored

How does Carbon-X perform on DNA benchmarks?

All scores are self-reported by Hugging Face. Carbon-X ran with thinking disabled. Competitors ran at their best reasoning effort.

Benchmark	Carbon-X	GPT-6.1 Sol (Max)	Opus 5.5 (Max)	Kimi K3 (Low)
BioReason Coding	74.9	71.0	70.3	53.9
BioReason Non-SNV	85.1	91.7	94.8	65.3
GenomeQA	63.6	67.2	62.2	52.0
NextBase	39.4	32.9	1.1	30.6
FrontierVEP	70.4	74.9	76.2	50.1
Average	66.7	67.5	60.9	50.4

Carbon-X sits 27 points above Qwen3-14B and 0.8 points below GPT-6.1 Sol. It leads on coding-variant effects and next-base prediction. Frontier models still win on complex variants and single-base variants.

Refusals shape these numbers. On NextBase, Opus 5.5 falls from 17.7% at low effort to 1.1% at max effort as refusals rise. Gemini 4 Argon drops from 58% to 38% on FrontierVEP as effort increases.

Carbon-X also keeps general skills: 79.3% prompt-level strict accuracy on IFEval.

What does Carbon-X cost to run?

Hugging Face prices Carbon-X at measured throughput on an H200 at $5 per hour. On that basis, it reports about 1/1,800 of GPT-6.1 Sol’s inference cost per problem. Scoring the 2.4 million ClinVar variants of uncertain significance would cost about $300. The same job costs $32,000 to $4 million on frontier models.

Carbon-X also works as a sub-agent. Kimi K3’s DNA index rose from 49.4% to 60.5% when it consulted Carbon-X.

How do you deploy Carbon-X?

vLLM:

vllm serve HuggingFaceBio/Carbon-X --trust-remote-code

on 1 x 80 GB GPU.

Transformers: v5 or later, with

trust_remote_code=True

for the DNA tokenizer.

llama.cpp: the official Carbon-X-GGUF repo needs llama.cpp b11742 or newer. Older builds tokenize DNA wrongly.
Agents: the repo ships an OpenAI-style tool, an Inspect agent and a

carbon-dna

skill for coding agents.

Keep

enable_thinking=False

. The model was post-trained and evaluated that way.

How does Carbon-X compare with other DNA and general models?

Feature	Carbon-X	Qwen3-14B	GPT-6.1 Sol	Evo 2 40B
Developer	Hugging Face + partners	Alibaba Qwen	OpenAI	Arc Institute
Parameters	14.8B	14.8B	Not disclosed	40B
Context	40,960 tokens	32,768 native, 131,072 with YaRN	Not disclosed	Up to 1M sequence length
Input	DNA + English	Text	Text (general-purpose)	DNA only
Answers in English	Yes	Yes	Yes	No
License	Apache 2.0	Apache 2.0	Proprietary, API only	Apache 2.0
DNA average (HF eval)	66.7%	~40.0%	67.5% (Max)	Not evaluated
BioReason Coding	74.9%	Not disclosed	71.0%	Not evaluated
Price	Open weights	Open weights	$2 / $10 per 1M input / output tokens	Open weights

Key Takeaways

Carbon-X is a 14.8B open model that reads DNA and answers in English.
It averages 66.7% on 5 DNA benchmarks, 0.8 points behind GPT-6.1 Sol.
It leads every tested model on BioReason Coding (74.9%) and NextBase (39.4%).
It runs on 1 x 80 GB GPU, or a 15.8 GB Q8_0 GGUF.
Splice-site accuracy is 29.8%, and it is not clinically validated.

Check out the model card, release blog, GGUF weights and GitHub repo. Also,feel free to follow us on**Twitterand don’t forget to join our150k+ML SubRedditand Subscribe toour Newsletter. Wait! are you on telegram?now you can join us on telegram as well.**

Need to partner with us for promoting your GitHub Repo OR Hugging Face Page OR Product Release OR Webinar etc.?Connect with us

Asif Razzaq

Website|+ posts Bio ⮌

Asif Razzaq is the CEO of Marktechpost AI Media Inc.. As a visionary entrepreneur and engineer, Asif is committed to harnessing the potential of Artificial Intelligence for social good. His most recent endeavor is the launch of an Artificial Intelligence Media Platform, Marktechpost, which stands out for its in-depth coverage of machine learning and deep learning news that is both technically sound and easily understandable by a wide audience. The platform boasts of over 2 million monthly views, illustrating its popularity among audiences.

$uv pip install omni-parse-bench**✓text✓tables✓layout→ scored per page Star on GitHub→**Sponsored

Previous articleResearchers from Stanford and UC Berkeley Introduce TokenGate: Token-Gated Attention Makes Long-Context Prefill Up to 11.3x Faster

Asif Razzaq