Claude 作为 Anthropic Claude Science 设置中的智能体自主完成了整个蛋白质设计项目,设计出的分子经实验室测试验证有 17 个能与蝎子神经毒素结合。该项目由金融机构 Citrini Research 发起,测试在 Adaptyv Bio 和 Twist Bioscience 进行,Anthropic 尚未将其称为抗毒素。
Claude did the protein scientist’s job and came back with 17 molecules that grip scorpion neurotoxins.
Claude, running as an agent inside Anthropic’s Claude Science setup, ran the whole protein-design campaign itself:
it picked which patch of each scorpion toxin to attack, drove 12 protein-design programs, set its own scoring cutoffs, and chose 180 molecules out of the 318,484 it generated for physical synthesis, and 17 of the 211 designs tested bound their toxin at Adaptyv Bio and Twist Bioscience.
Citrini Research, a finance firm with no lab and no protein expertise, asked for this work, and Claude designed proteins that two labs confirmed latch onto scorpion venom toxins.
Scorpion stings kill more than 3,250 people a year, so the prize is real, if this method works. However, Anthropic is not calling this an antivenom, because the test that would justify the word has not been run yet.
来源:Rohan Paul · x.com